Taken from: https://outof.games/yu-gi-oh/guides/200-introduction-to-cybernetic-successor-yu-gi-oh-master-duel-structure-deck/
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Bare Essential Starting Hand
Cyberdark Claw + Any Spell/Trap to discard + Any "Cyber" Monster to discard + Any Cyberdark Monster to Fuse
- Activate Cyberdark Claw to add Cybernetic Horizon.
- Activate Cybernetic Horizon by dumping any 2 "Cyber" Monsters from Deck and Hand to GY, including one Cyberdark. Search Cyber Dragon Core and send Cyber End Dragon to the GY at resolution.
- Normal Summon Cyber Dragon Core, enabling you to add Cyberdark Realm to hand.
- When activating Realm, Cyberdark Cannon will be the next Monster to search.
- Now activate Cannon to replace it with Cyberdark Chimera, which lets you Fusion Summon by banishing materials from the GY.
- Thanks to Cyberdark Realm we have a second Normal Summon for Cyberdark Chimera.
- Chimera now uses its effect to discard the Spell/Trap we started out with, which gets us to Power Bond (Power Bond must be in the Deck for this to work).
- A total of 3 Cyberdark Monsters are now in the GY, Chimera is one on the field, and one was in the starting hand. This means Power Bond can use all 5 to bring out Cyberdarkness Dragon.
- The effect on Summon will let us equip Cyber End Dragon to it and voilà, the unaffected by activated effects 5,000 ATK Monster hits the field.
"Ideal" Starting Hand
Cyber Emergency + Cyberdark Cannon + Any Spell/Trap to discard
- Emergency adds Core.
- Core adds Realm.
- Realm adds Claw.
- Claw adds Horizon.
- Cannon adds Chimera.
- Horizon is used by discarding Chimera from hand and Core from the Deck.
- Another Chimera will be added, and Cyber End Dragon hits the GY.
- Chimera triggers in the GY, allowing a fourth Cyberdark Monster to be sent from the Deck to the GY.
From there onward it's the same routine as above. In this variation, four Cyberdarks are in the GY, since Chimera was added twice, allowing its effect to send another. When you start out with more combo pieces than needed, consider if you can afford to search Cyberdark Invasion for added disruption.
One last idea to close the combo section out on: It's not always correct to go all in. A potential plan B could involve passing just with Cyberdarkness Dragon. The possibility to negate any effect up to the amount of equipments it has, is worth looking into. Even for something as simple as an activated Maxx "C", ending on a single negate might prove more detrimental than granting the opponent another draw.